Wednesday, May 6, 2020

Stem Cells Research For Disease Modeling And Drug...

Stem Cells in Research without the Ethical Issues: Ways around Embryonic Stem Cells Deborah Baluyot Western Governors University Abstract: Using various academic journals and articles found online (Internet), this paper seeks to cover the use of human stem cells (hSCs) in research for disease modeling and drug development. Specifically, the ethical controversies that come with using embryonic stem cells (Lo Parham , 2009) and possible ways to get around them, will also be reviewed. Induced pluripotent stem cells in particular have the potential to replace the use of embryonic stem cells as they work in very similar ways. While there is some debate on how induced pluripotent stem cells still bring up some ethical issues (Alberta, 2009), they aren’t as heavy in comparison to that of embryonic stem cell usage. Also covered is the need for funding for stem cell research Keywords: ethical, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), disease, drug development, research Stem Cells in Research without the Ethical Issues: Induced Pluripotent Stem Cells instead of Embryonic Stem Cells Over time, the use of human stem cells has proven to be monumental in research, particularly in the field of disease modeling and drug development for treatments of diseases. However, there are many barriers that come with using human stem cells, specifically embryonic stem cells (ESCs), mainly due to the fact that they must come from eitherShow MoreRelatedStem Cell Research Should Not Be Allowed1170 Words   |  5 PagesBatten Disease. Our community came together in support of â€Å"Jaylen’s Journey†. In honor of Jaylen and to aid his family in covering medical cost, the community held a 5K, sold t-shirts, and created a Facebook page. Batten Disease attacks the nervous system and vision loss occurs. Currently, a cure does not exist for Batten Disease, and without surgery, Jaylen is expected to die before he is 16 years old. The hope of a cure for Jaylen comes through an experimental surgery with the use of stem cellsRead MoreStem Cells Essay1746 Words   |  7 PagesIntroduction The use of stem cells can advance drug development, knowledge of disease, patience specific disease treatment, and can bypass the limits of mouse-models for research. According to the National Institute of Health (1), stem cells are unique in the following ways: they can divide and renew themselves for long periods, they are unspecialized, and they can give rise to specialized cell types. The uniqueness of these stem cells allows for the testing of new drugs, cell-based therapies and theRead MoreStem Cells And Its Effects On Human Cells2106 Words   |  9 PagesStem cells are undifferentiated cells within the body that are defined by their ability to self renew and differentiate into specialized cells (1). Stem cells function in body tissues as a repair mechanism, with an unlimited ability to divide and restock cells as needed by the body. Each time a stem cell divides, the new cell formed can either remain a stem cell or differentiate into a specialized cell, such as a brain cell. Traditionally, there are two main types of stem cells: human embryonic stemRead MoreThroughout centuries, scientists have discovered new and improved ways of curing certain types of1500 Words   |  6 PagesThroughout centuries, scientists have discovered new and improved ways of curing certain types of diseases with medical treatments that continue to be discovered. When newly discovered, many treatments and cures are controversial. Immediately, society questions whether or not these medical practices are reliable, safe, and ethical procedures. Such as electroconvulsive therapy (ECT), also known as â€Å"electroshock†, a medical procedure where patients who may be victims of schizophrenia or depressionRead MoreHuman Cells And The Human Body1747 Words   |  7 Pagesfiltration, toxins, and waste removal and maintaining and regulating the body’s pH. The researchers created kidney structures from induced pluripotent stem cells (iPS) called organoids which have the func tion and structural organization of a human fetal kidney in the first trimester. This study used the results of a previous study where human embryonic stem cells were differentiated towards a renal lineage. As a result, the progenitors for both collecting ducts and nephrons were generated from iPS. In thatRead MoreHuman Embryonic Stem Cells ( Hescs )1627 Words   |  7 PagesiPSC The interest in developing human embryonic stem cells (hESCs) as a regenerative medicine has been prospering due to its pluripotency and indefinite self-renewal capacity since first discovered in 19981,2. However, the method to harvest hESCs by destroying embryos raised ethical concerns and thus the progress of this therapeutics has been impeded for years. Alternative approach was not achieved until the discover of induced pluripotent stem cells (iPSCs) by integrating a combination of transcriptionalRead MorePre-clinical testing is performed to Good laboratory practice (GLP) and covers pivotal toxicology 1000 Words   |  4 Pagespreclinical research, scientists test their ideas for new biomedical prevention strategies in laboratory experiments or in animals. â€Å"Pharmacokinetics (PK) and pharmacodynamics (PD) can be seen as two sides of the same coin. PK and PD have a definite relationship, assessing how much drug gets to the site of action and then what that action is. Both activities are essential in the complete investigation of the interaction between the drug and body, and play significant roles in both drug development andRead MoreEthical Concerns Of Stem Cell Research1759 Words   |  8 Pagesfields within stem cell research and the one under the most scrutiny is embryonic stem cell research. To be able to use their stem cells without killing them has not been developed yet, so many articles on ethical concerns of stem cell research are focused on this specific topic. Many areas of science are treated as unethical, but stem cell research, which is considered the worst,could single-handedly reshape the world as we know it. Description of Stem Cells Unlike the other cells that make upRead MoreReview : Tissue Engineering And Tooth Regeneration1865 Words   |  8 Pagesclinical treatment. Some of the primary barriers preventing integration include cost and development of appropriate materials, limited current infrastructure, and ethical challenges. This review explores current uses for regenerative dentistry, as well its barriers and potential solutions to these problems. Oral tissue loss is a major problem both globally and in the United States, and can be caused by disease, trauma, and/ or congenital abnormalities1. In fact, tooth loss is the most common formRead MoreAnimal Testing And Its Effects On Human Health1146 Words   |  5 Pagesactivities are necessary to progress in medical research, in reality it does very little to improve human health and development. For decades, drug and chemical safety assessments have been based on laboratory experimentations involving rabbits, dogs, rodents, and other animals. Consequently, nine out of ten drugs proven safe and effective in animals fail when given to humans. Animal testing is unreliable and unnecessary and there are more effective research methods out there that do not come at the

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.